hello, I am new to Neuro Talk and was hoping there might be many here who have been on Tysabri for a year or more and can help me figure out if this is just me or not.

I have had 14 infusions and Tysabri has been very good at slowing my MS down, but lately I am starting to feel as though the initial effectiveness might be starting to decrease?

Just wondering if anyone else have noticed an increase in their rate of flares, symptoms, or disease activity after having a good long remission on Tysabri?

I think this concern was triggered by my recent flare. It was the first since starting Tysabri, and mild when compared to my previous flares, but makes me worry anyway.

Thanks for any related experiences! I hope I put this in the right spot, was gonna start a thread about it but saw the Tysabri sticky...