You just said exactly what I am thinking. While I would probably choose beta if I could guarantee no SE, the SE do scare me, especially with everything that is going on in my life right now. I can't afford the flu like s/s. Like you, I also have a hx of depression, and right now I am not on anything. I would LIKE to keep it that way, but if I choose an interferon, I would probably go on an anti-depressant as a preventative. My dad was on interferon during his cancer treatment, and while it is probably different with dosages and stuff, it made him CRAZY! He could only tolerate it for a week.

I am still researching. I told DH, if I have to make a choice NOW, it will probably be C, and when my life calms down a bit, and I can afford to test the waters with the SE, I may choose beta. I am also going to discuss all this with the specialist I am going to see and se what he has to say about it.

I am intrigued with the LDN though as well... and am thinking C may be the way to go because I am considering that. Working the the addiction field, I give an amino acid treatment and we deal with brain chemistry and how that affects addiction... so I am intrigued by the epinephrin, serotonin, dopamine, and all the neurotransmitters... which is one reason I am trying to stay away from antidepressants... I want my chemistry as close to God given as possible to see how *I* can effect it!

Thanks for your insight!!