A friend of mine is currently on Avonex and Copaxone at the same time, outside of the clinical trial. Just because the trial is not ongoing doesn't mean it isn't done.

Rebif is basically the same interferon as Avonex, just dosed differently.

It was suggested to me to add Copaxone to Betaseron when I was failing on Beta, but instead we added Methotrexate to Beta. I stopped that after a year as it was not doing me any good. I then switched to Tysabri but it was pulled from the market after I had two infusions.

Bottomline Brandon, injecting 2 DMT (disease modifying treatments - the new term) is not unheard of and more common than you might think. There are a lot of Neurologists who think outside the box these days to treat their patients. I hope you get some relief soon.

IViG is another option you might want to look at as well as Cytoxan before moving to Novantrone. Keep us posted on your progress.