Nurse Nancy
The way Namenda was explained to me by a pain mgmt doc (near as I can recall) was that it changed the brain chemistry and the way messages were relayed through the CNS. That had brought relief to a couple MS patients he had treated. He wasn't sure it would help me, but was willing to prescribe.
I'm basically just grasping at straws for relief. Since my doc is against LDN. I'm at my wits end and my hands hurt ALL the time and it gets worse when I use them.
HTH
I also PM'ed you with more info.