Thanks, Erin.

As I was thinking about it last last there are two points about the Criteria I want to emphasize.

First, the neurologist must have a clear view of the pattern of symptoms and emerging neuro exam abnormalities before he ever approaches the MRI for additional evidence.

Second, is that the Criteria only deal with the T2 Hyperintense or enhancing lesions. That is also to say that they only deal with the immune-inflammatory part of our disease. This is the part that is directly responsible for our relapses and remissions (via demyelinationa and repair). But, we know that there is a separate and unclearly related part of direct nerve cell and nerve fiber degeneration/death that is more likely responsible for our accumulation of permanent dsability. There is also the destruction of gray matter via T2 lesions.

So when we are able to see the cellular degeneration via our imaging techniques, the Criteria will have to change to include them.

Quix