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Originally Posted by Natalie8
What about black holes? If a person has CIS and the MRI comes back showing T2 lesions, enhanced lesions, and black holes (like me!) isn't that a dissemination in time even without a second clinical attack?
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Natalie, the Black Holes are seen in the T1-weighted images. They are the accumulation of areas of direct axonal (nerve fiber) degeneration. These correlate very well with both the accumulation of disability and with brain atrophy. Interesting enough, they are not so much the product of the inflammatory demyelinating and remyelinating lesions. So the Black Holes are NOT just the progression of the T2 lesions that the neuros talk about.
Quix