There are still people taking Zoloft. Just not as many as people taking the newer drugs. Side effects and the fact that the newer drugs work better for more people. Zoloft is one they use for kids/teens when necessary because they have a lot of information on its use. Trazdone is a very old one. That one's been around since...good grief...the 1960's? Trazadone is often given for sleep as well to people with anxiety and depression issues. The newest one on the market, unless I've missed something, is Cymbalta. Cymbalta has the added good side of pain relief for certain conditions.