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Old 10-23-2006, 11:16 PM
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Mari Mari is offline
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Join Date: Sep 2006
Posts: 18,914
15 yr Member
Thumbs up Study: The ketogenic diet may have mood-stabilizing properties.

hi there,
Here is another reason to go low carb!
Mari

The ketogenic diet may have mood-stabilizing properties.

Med Hypotheses. 2001 Dec;57(6):724-6. Related Articles, Links
El-Mallakh RS, Paskitti ME.

Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Kentucky 40292, USA.

Quote:
The ketogenic diet, originally introduced in the 1920s, has been undergoing a recent resurgence as an adjunctive treatment for refractory epilepsy, particularly in children. In this difficult-to-treat population, the diet exhibits remarkable efficacy with two-thirds showing significant reduction in seizure frequency and one-third becoming nearly seizure-free.

There are several reasons to suspect that the ketogenic diet may also have utility as a mood stabilizer in bipolar illness.

(1) These include the observation that several anticonvulsant interventions may improve outcome in mood disorders.

(2) Furthermore, beneficial changes in brain-energy profile are noted in subjects on the ketogenic diet. This is important since global cerebral hypometabolism is a characteristic of the brains of depressed or manic individuals.

(3) Finally, the extracellular changes that occur in ketosis would be expected to decrease intracellular sodium concentrations, a common property of all effective mood stabilizers. Trials of the ketogenic diet in relapse prevention of bipolar mood episodes are warranted.
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