Twink - Another thing to keep in mind is how you use your space.

If you love to cook and do a lot of cooking find solutions that will assist you the best so that you can continue making those gourmet meals. A prep center with a small sink in it and a small under the counter refrig that is lower is more useful to those in a wheelchair as well as those of us who can't stand for long periods.

If you love to bake, think of solutions that will assist you with baking. Appliance lifts are great for this if you have a spare base cabinet to use.

A formal dining room that will rarely get used is a waste of space as well as a waste of energy (something us MSers need to conserve) to have to clean. A nice craft space, home office, exercise room, expanded living, etc. would be more useful and practical if you don't use the formal dining room.

If you like luxurious baths, put a tub in that will accommodate you. I did have a client that had a spinal cord injury and was paralyzed from the waist down. She wanted to take out her shower and put in a Jacuzzi garden tub. However, most of the ones she found had the faucets on the outside of the tub so that if she was trying to get in the faucet was in the way. We ended up putting a pony wall (1/2 wall) and running the plumbing through there so that she was able to access the faucets easily as well as get in the tub easily.