I had it bad on the palm of my right hand a few months before I was dx with MS. I know it was my MS acting up but I don't know what triggered it.
Have you tried anything with Olive Oil or Rosemary Oil in it? I know there are OTC creams with tar but they smell so bad and they didn't really help me.
I use a lotion from Perlier called "Hemp with Rosemary Oil". It's made from Hemp seed extract and oil of rosemary. I love it and won't be without it. My psoriasis has cleared up (my hand is the only place I had it) and hasn't come back.
Here's the website if you're interested in trying it:
http://www.perlier.com/home.php