Pantos,
Quote:
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Azathioprine has an extremely short half-life itself, minutes, and its active derivatives have a half-life in the hours (1-3). I would be very surprised if it exerted any effect on the immune system months after discontinuation.
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Yet Biogen tried to infer to this patient's family that, because of Azathioprine and other drugs the patient had used months earlier, this was the main reason he ended up with PML!!!
Harry