Brenda,

I would not use Tysabri as a melanoma survivor.

You quality of life is a balance between dealing with the existing bouts of pain versus the potential for melanoma.

I think that the worries you would experience relative to melanoma would impact the quality of your life more than dealing with the existing levels of pain.

If I was in the same position, I would avoid Tysabri and pursue pain medication along with a mild course of a tolerable MS medication.

I would not tke the risk...

-Vic