I am still wondering if this drug has any utility in PD---seems it is an glutamate antagonist. and I wonder what the chapter title "drug discrimination studies" includes (see link at end of posting). it is not as if several of the prescribed dopamine agonists do not have hallucinatory adverse effects for some individuals. and if ibogaine could be used in a dosage that does not induce hallucinations, perhaps it could be used to increase GDNF without the need for implantation of catheters into the putamen or wherever it is those are placed. I find it fascinating that an entire book was written about this substance, and yet nothing further has developed. Yes, I know it is not patentable. And yet, GDNF is now being studied for alcohol addiction. Why not ibogaine? and yes, this natural occurring substance may have dire effects, even "fatal ones" as noted in the media alert--but so do ALL drugs. Is this substance more fatal than some of the pharmaceutical drugs on the market today? what was that quoted # of patients who die each yr due to drug adverse effects?
http://www.ibogaine.org/apcontents.html