I'd like to compare notes a minute about on/offs. Not many seem to deal with them on the forum.
In particular, I wonder if your experience would mesh with an explanation of stress as a trigger. I have noticed that I can sometimes find myself going into one of these states due to stress, remove the stress and relax, and move back to normal without any more meds.
I also find that these states do not respond to more medication. In fact, there seems to be a need for a certain amount of time to pass. That would be consistent with stress hormones droping.
Quote:
Originally Posted by kk13
Don't Ask...After 20 years with the disease, I got 'em all!!! Or almost all.
The two major problems I have are the "textbook" or "classic" advanced PD problems: Dyskinesias: too much of a good thing, and "on/off" fluctuations: meds stop working long before next dose and at other unpredictable, inexplicable times throughout the day.
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