Most folks do not know much about this but NGF Nerve Growth Factor is great stuff to have in sufficient quantity to take care of those small? brain repair jobs common to MS folks.
If you are LOW in Vitamin D then you are probably LOW in NGF Nerve Growth Factor also.
I probably should start a new thread to elaborate on this topic.(Nerve Growth/Repair)
Suffice it to say that Vitamin D makes the body make NGF as stated in the below abstract.
http://www.copewithcytokines.de/cope.cgi?key=NGF (a GREAT sources of my info)
This is why I take 4000 IUs of Vit D3 supplement each day. The excess is GOOD for MS folks because our NEED is greater.
jackD
http://www.ncbi.nlm.nih.gov/pubmed/9...ubmed_RVDocSum
Quote:
1: Nippon Yakurigaku Zasshi. 1997 Oct;110 Suppl 1:39P-43P.
[Novel pharmacological activity of a vitamin (novel pharmacological action of vitamin D)][Article in Japanese]
Fukuoka M, Ohta T, Kiyoki M.
Teijin Institute for Bio-Medical Research, Tokyo, Japan.
The endocrine system to maintain calcium homeostasis involves the active vitamin D, as well as parathyloid hormone (PTH). Based on this 'classical' calcium-regulatory function, 1,25-(OH)2D3 and 1 alpha OHD3 was developed as the drug for vitamin D resistant rickets, renal dystrophy, and osteoporosis. Psoriasis is a chronic skin disease which is characterized by hyperproliferation and abnormal differentiation of epidermis. As an anti-psoriatic drug, 1,24R-(OH)2D3 has been on clinical use. The efficacy for psoriasis is explainable by the differentiation-inducing activity of this compound. 1,25-(OH)2D3 was also reported to suppress proliferation and induce differentiation of tumor cells including breast cancer, colon cancer and so forth, suggesting the possible therapy of malignant tumors.
 In immune system, active vitamin D3 exerts various effects; 1,25-(OH)2D3 suppresses proliferation and cytokine production in T cells and antibody production in B cells. Animal models of autoimmune diseases and skin-graft suggest active vitamin D becomes a novel immuno suppressant.
 Since 1,25-(OH)2D3 induces the synthesis of nerve growth factor (NGF), it will be a new therapy for the treatment of neuronal degenerative diseases.
PMID: 9503403 [PubMed - indexed for MEDLINE]
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