note that the findings were in age range 24-54 --young onset PD. Not for ages >54, which accounts for sporadic onset PD, the greatest % of all PD cases. Dr. Xuemei Huang, MD, found low LDL levels had a positive correlation with PD. She has designed a clinical study to determine if statin use is associated with the onset of PD; she has not found funding to date.

the mavelonate pathway is blocked by statin drugs; one of the sort of "incidental" findings is that statins interrupt the pathway to production of "dolichols". The substantia nigra is composed mainly of fats; the largest % of fats making up the SN are dolichols. Does it matter clinically if one blocks the pathway that accounts for the largest composition of the Substantia nigra structure? Who knows? Who would ever fund this study?
and that is just one of the pathways blocked by statins, there are many others which accomplish essential biological functions.

In some reports, statins are found to cause muscle aches in a large % of patients. madelyn