I too take one tablet of Azilect per day and have had good results. I had first PD symptoms in 9/2000, was diagnosed 2 years later and started Azilect soon after it was approved. I am almost symptom free most of the time and had to cut back on my Sinemet because of the Azilect. I also take Amantidine. I still work full time as a teacher and hope to work forever, if possible.