Hello Brian - Advil PM is used for occasional sleeplessness when associated with minor aches and pains. The regular Advil is used for headaches, muscle aches, etc. Some people use Tylenol versus Advil and there is a Tylenol PM (this did not work for me). It is an OTC product. I do not know how well either one would interact with any of the other medications that all of us take. You could use one of those drug comparison sites that have been mentioned to check it out.

Diana