The TERMS trial consisted of 22 visits in a 13-month period...five of which I received the vaccine.

Each visit I had a blood draw for testing of MRTCs, chem panel, STDs, west nile virus, hep ABC, and some other things, an MRI, a complete neuro exam, PASAT, EDSS, peg test, eye exam, and a questionnaire. Oh yeah and a pregnancy test and UA.

My last vaccine was Sept 21st, my last visit in the trial was April 1st. I had an MRI, blood draw, complete neuro exam and that visit also consisted of the first blood draw for the MRTC testing.

My EDSS, from what I can remember, waivered from 1.0 to 3.0, depending on how I was feeling. Mostly sensory changes, except when I had the flare last August and it included motor changes, balance and dexterity. I could barely pick up and hold onto the pegs.

My last visit on June 27 consisted of a blood draw and a complete neuro exam. No MRI, none of the other stuff.

I cannot answer your question on how long we are to receive the vaccine...life long or if there is an endpoint. I believe Tim is on his 22nd vaccine. But they are 6-8 weeks apart for a period of time, and then so many months off, and then 5 more vaccines after re-evaluation of the epitope/peptide for the vaccine. (he explains it a whole lot better than I do!) I am still trying to figure out why I am not producing MRTCs....

Does that answer your question? Or have I confused you even more?

As for anyone else not producing...I have no clue.