I'm totally with ya Sally!! The so-called "approved" injectables did a number on me and I just felt miserable all the time. Guess I've been on LDN about four years, think it was about a year after you started that I finally convinced my neuro to prescribe it since all else failed.

Even though I have the nerve pain, it's always been there, and the neuro said at my last checkup, I seem to be stable. Just wish he would have let me take it before becoming SPMS.

Like Sally, the 4.5 mg. caused extra stiff legs so went back to 3 mg and here I've stayed. At the beginning my legs worked some better but the main improvement was in bladder function. I still have to go before I really have to -- LOL -- but without the LDN it's a total disaster. Yes, the well-being feeling is there too with NO side effects, plus it's sure alot cheaper than anything else!!

Try it......maybe you'll like it!!

Thanks for the info Sally!