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Old 07-21-2008, 09:00 PM
caldeerster caldeerster is offline
Junior Member
 
Join Date: Aug 2007
Posts: 81
15 yr Member
caldeerster caldeerster is offline
Junior Member
 
Join Date: Aug 2007
Posts: 81
15 yr Member
Default Why no trials yet of tnf-a and il-1 antagonists?

Recently, over the past few years, there have been numerous papers written in reputable neuro journals by reputable MDS's linking the onset of PD with cytokine inflammation, specifically tumor necrosis factor and interleukin-1.

Can someone more familiar than I with the various groups that lobby for more NIH funding or someone who knows the workings of the NPF or FOX kindly explain why, to my knowledge, there has not been ONE trial begun which explores this hypothesis?

There are tnf-a antagonists that already exist. There are also il-1 antagonists that already exist. The drugs are there. There are minimally invasive ways to get these drugs into the brain.

Why is this not being aggressively explored? Anyone know?
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