My condition in over 2 years has caused B&B paralysis and I use Valium and self cathing for the bladder, but although I have tried every OTC and RX known to man, nothing has worked and in 2 years I have went from daily to sometimes 5-7 days causing no end of pain and misery...so anyway I have seen same commercial over and over and decided why not try it, can't hurt, it is Activia like a yogurt or a smoothie by Dannon so a week ago I tried the smoothies and they worked somewhat and 2 days ago I broke down and got a 4 pack of the yogurt and I ate 2 of them, and I was on day 5 or 6, and I had a very large normal BM all on my own and that for me was a miracle, no Rx, just a slightly more expensive yogurt and I will go that route for awhile hoping that one a day may no doubt regulate me again and maybe I am not the only one that has this problem which I seriously doubt! Gross I no but I feel sure it is a very real probel for most of us ad I want as few pills as I can in my life so for me this is very exciting and yet another subject unable to share with family!