First, the link that *******/Godfather/Bridgeman, or whatever the nom du jour, is actually pretty good as a general overview. With so many chemicals around and so many possible interactions, any list is going to be limited.

But i would like to complicate things a little. Inflammation can open the "tight junctions" of the epithelium (the "lining" of the blood vessels) at both the brain and the GI system. As a result toxins that were supposed to leave the body can be absorbed into the blood and sent to the brain. Even more maddening, when the load gets too heavy on the liver (detox central) a bypass system (the portal shunt) kicks in and the contaminated blood recirculates adding even more toxic burden.

Which brings up the subject of constipation. We all know that it is a feature of PD. What I would like to know is which came first? For myself, I've been "a little slow" all my life. Anyone else care to share intimate details?

If a slow GI system comes before PD, that is a major bit of information, especially for our children.