View Single Post
Old 08-24-2008, 12:33 PM
lady_express_44's Avatar
lady_express_44 lady_express_44 is offline
Grand Magnate
 
Join Date: Aug 2006
Location: Vancouver, Canada
Posts: 3,300
15 yr Member
lady_express_44 lady_express_44 is offline
Grand Magnate
lady_express_44's Avatar
 
Join Date: Aug 2006
Location: Vancouver, Canada
Posts: 3,300
15 yr Member
Default

Quote:
Originally Posted by lady_express_44 View Post
The primary clinical endpoint for the trial is defined as a statistically and clinically significant increase in the time to progression of the disease as measured by the Expanded Disability Status Scale (EDSS), in patients with HLA-DR2 and/or HLA-DR4 immune response genes (up to 75% of all MS patients are HLA-DR2 and/or HLA-DR4 positive)."
Another thing that is really exciting about this treatment, is the PRIMARY ENDPOINT will be measured by disability progression, not number of relapses and/or enhancing lesions. That means this might significantly impact the overall disease process, unlike the CRABs and Tysabri which focus their success mostly on the inflammatory process (a more transient measure of the disease).

Cherie
__________________
I am not a Neurologist, Physician, Nurse, or Hairdresser ... but I have learned that it is not such a great idea to give oneself a haircut after three margaritas
.
lady_express_44 is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
barb02 (08-24-2008), dmplaura (08-24-2008), Ivy2 (08-25-2008), Kitty (08-24-2008), MSacorn (08-25-2008), SandyC (08-24-2008)