I'm on that 'weekly hummer shot' but I am overweight so there's a lot of fat for it to go through and it doesn't hurt. But I prefer giving myself my own shot. I think of it like this. I, myself am doing something to combat this disease. I, myself have the upper hand. May sound a bit corny and I may not feel this way if my MS were worse but it works for me now. My husband ws a medic in the Navy so I have my built in back up.