Quote:
Originally Posted by jackD
Vitamin d levels should be on the HIGH side for MS folks.
That usually means taking some Vitamin D3 in the amount of 4,000/5,000 IEUs daily.
That 50,000 Vit D stuff is Vitamin D2 which is the ONLY Rx stuff available. It may work and fix the problem BUT it is a poor version for HUMANS.
Taking Vitamin D3 is MUCH MUCH BETTER.
Vitamin D3 levels at 100 will greatly lower MMP-9s (the stuff that makes holes in the BBB Blood Brain Barrier and then cuts myelin into three pieces for lunch by other invaders who get into the brain via the hole it just made.)
ALSO - VERY IMPORTANT - at 100 level it (Vitamin D3 and related components) causes the BRAIN to really produce lots of NGF - Nerve Growth Factor. Great stuff for those small MS Brain repair jobs. (pun intended)
The upper limit for us poor sick MS folks is 10,000 IEUs. This is also the upper limit for Normals but I wanted the MS folks to feel SPECIAL.
I can post all the studies but it is all in NLM http://www.pubmed.gov and since I have posted this many times for the last 10 years I would prefer someone else visit the magic place I get all this good info.
jackD |
Here is an example of what you get if you do a search on ("vitamin d3 10,000)
jackD
Quote:
1: Am J Clin Nutr. 2007 Jan;85(1):6-18. Links
Risk assessment for vitamin D.Hathcock JN, Shao A, Vieth R, Heaney R.
Council for Responsible Nutrition, Washington, DC 20036-5114, USA. jhathcock@crnusa.org
The objective of this review was to apply the risk assessment methodology used by the Food and Nutrition Board (FNB) to derive a revised safe Tolerable Upper Intake Level (UL) for vitamin D. New data continue to emerge regarding the health benefits of vitamin D beyond its role in bone. The intakes associated with those benefits suggest a need for levels of supplementation, food fortification, or both that are higher than current levels. A prevailing concern exists, however, regarding the potential for toxicity related to excessive vitamin D intakes.
The UL established by the FNB for vitamin D (50 microg, or 2000 IU) is not based on current evidence and is viewed by many as being too restrictive, thus curtailing research, commercial development, and optimization of nutritional policy.
Human clinical trial data published subsequent to the establishment of the FNB vitamin D UL published in 1997 support a significantly higher UL.
We present a risk assessment based on relevant, well-designed human clinical trials of vitamin D. Collectively, the absence of toxicity in trials conducted in healthy adults that used vitamin D dose > or = 250 microg/d (10,000 IU vitamin D3) supports the confident selection of this value as the UL.
PMID: 17209171 [PubMed - indexed for MEDLINE]
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