Hi Barb..

It sounds like you want what we all want, at this point, A sure thing. But, alas, LDN is not that and neither is Imuran or any of the other DMDs.
As far as going off all other meds, before you start LDN, I wouldn't recommend it. Like Cherie, the only med I was on was an AD and I am still on one.....Although, I have heard of many LDNers, being able to drop some if not all of their symptom meds, after being on LDN for a time.
We can only give you our experiences with LDN and we have done that, ad nauseum..

It has done much to help many, but not everyone has a great experience with it. I hope you do, but you won't know until you try it.
If it were me, I would not take Imuran with LDN, but that's just me.
I wish You All The Best Experience with LDN...
