It takes Avonex about 6 months to become fully effective. Use a smaller needle size. Try some EMLA cream type stuff to numb injection area. I was on Avonex for over 10 years. The side effects for the mix yourself were gone for me after 4 weeks.
Here is my posting on.."maximizing INTERFERON-Beta effectiveness" on another MS Board. It is THREE pages long.
http://www.msrefugees.proboards82.co...ay&thread=3770
jackD
P.S I was pleasently surprised to find my Doctor Christopher T. Bever, Jr at the Maryland Center for Multiple Sclerosis, 22 S. Greene St., N4W49, Baltimore, MD seems to feel that the MMP-9 approach may have some merit. His editorial is very interesting.
http://home.ix.netcom.com/~jdalton/E...ver-mmp-ms.doc