Out of India~

Results: Of the 63 siblings of 48 index cases studied, 15 tested positive for anti-tTG; of these 13 had celiac disease. Three tested borderline for anti-tTG; none of them had CD. Of the 45 anti-tTG-negative subjects, two agreed to undergo biopsy; one of these had features of CD. Overall, 14 of 63 (22%) siblings had CD, including 8 who had no symptoms suggestive of CD. Conclusions: CD is common among siblings of patients with CD in Punjab and may be asymptomatic.
Prevalence of celiac disease among siblings of celiac disease patients. PMID: 17090839 Sept 2006