New, or worsening of existing symptoms, lasting longer then 24 - 48 hrs, indicates an attack . . . unless you have an infection going on somewhere. Have you been checked for a UTI, had a cold lately, have problems with your teeth, etc. ...?

The burning ~ is it like fire burning on the skin, or muscle burning? If they feel like they a blow torch is on them, you MIGHT want to try an antihistimine. I have no idea why Benadryl has been helping me with that (and the pin-prick itching), but I guess some allergic reaction is stirring up my neurological symptoms.

How long have you been on Avonex now?

Cherie