I've been taking it since December 2000 since I had my hysterectomy. I take a very low dose of plain estrogen, .625 mg. It helps me I suppose, but I've kept taking it so I don't know what would happen if I stopped. I'm afraid to stop it because after my hysterectomy I had a biggie of a relapse with the MS,affecting my walking, energy and bladder and followed by at least a year of spasticity.

I figure that it helps the MS, and it's such a low dose, I'm staying on it, at least for the time being.