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In Remembrance
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Join Date: Aug 2006
Posts: 3,772
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In Remembrance
Join Date: Aug 2006
Posts: 3,772
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PD is like a car with no steering wheel
A small stone sends us careening away. Same with speeds above a crawl. The car runs, the muscles work. The results are hard to control.
So, the sinemet that worked yesterday may not today for reasons that are darned hard to see. Chronobiology (circadian rhythms) has some clues as levels of hormones, neurotransmitters, cytokines, etc go up and down during the day.
Stress levels are big factors. How much sleep, too.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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