Marion, I lost 30 lbs, but that wasn't until I was able to get off antidepressants a year after being on LDN. I think the use of them (A/D's) caused me to gain weight over a period of about 2 yrs, and the ability to ditch them caused me to lose it. The weight just "fell off" though, with no effort what-so-ever on my part.

Tree, I've heard it said the probability of symptom relief might be dependant on how long we've had that symptom. I don't know if I believe that because I managed to get rid of the claw hand that I had had for 5 yrs. Most of my other symptoms though, were only about 2 yrs old . . . but most had been consistent and very debilitating throughout that time.

Some changes are very insidious though. I've heard people say that one day, after several months on LDN, they suddenly realized that hadn't used their cane for short distances in a long time. I think it's kinda' like we don't always notice as things slowly progress (with the disease process), and we don't always notice as things slowly improve (from LDN) either.

Not everyone experiences substantial symptom improvement either, for whatever reasons. I looked at symptom improvement as a "bonus" because I was taking LDN to HOPEFULLY affect my disease progression and relapse rates.

Cherie