I really think it all depends. Each medication we take has side effects. Some people get lucky and don't experience them. Others do. But you have to weigh the good with the bad in most cases.

Take for example, Clonazepam. It's done what no other drug has done for me, to date. Dulled the pain of my burning mouth. It also dulled the heck out of the burning pain I experience elsewhere with MS, and has actually made me 'headache free' as a result.

Clonazepam carries a list of side effects: http://bipolar.about.com/cs/sfx/a/sfx_klonopin.htm

It can also be habit forming. Thing is, this is the risk versus return for me. It's made me feel as a person "Without MS" (my symptoms are mild, mainly sensory which includes a pain aspect). For me so far at a very small amount, it's honestly a wonder drug. I take a very tiny amount at night, and it also helps me sleep peacefully.

Is it for everyone? Certainly not. It's wonderful in my case. I haven't experienced side effects thus far, thankfully.