Ra,
I'm also glad to hear that the powdered form works better for you. I seem to also ride the Avonex roller coaster, sometimes it is a breeze, other times it really kicks my butt, like this weeks shot. I was miserable, fever, muscle aches and nauseated (sp?) also. The nausea may have had something to do with the aleve and advil I was taking not sure. Other times, I have no issues at all with the shot. I've been doing this for 2.5 years and haven't got it figured out yet!!

When it's time for my shot though, I seem to be retaining a lot of fluid, it seems like my ankles swell, etc and my legs feel like I'm walking through water. After the Avonex shot and my night of misery this goes away until the next week around shot time again. I don't know if the avonex is helping me with this or it's the aleve and advil helping with inflammation.

Good luck,
Kathy