However, only YOU can decide what does or doesn't work for you at any given time. The only way you will find out is to give some things a try.
Simply put, meds are either going to work, work too well, work sort of well or not work at all.
I've been given some meds that I KNEW from pill two that IT and I were not going to get along together well at all. For others they either took a time to really work or a time to bring out those pesky side effects we all hate.
Also important in my opinion, is to be aware that taking a bunch of 'pills' in the AM and then in the PM isn't always the best way to go. For example, calcium taken with many meds can interfere or enhance the good/bad effects of the med.
Don't let that put you off though. You have to try and have a life. Finding the right meds to get you there are key to getting that and keeping it!
As for depression? Well, who here isn't a bit depressed with the constants of PN? Just keep looking around and finding those good things [blessings, maybe?] that you can count. They are there, tho they mite be hiding.

's and good things to you and soon - j