Kelly, You get the optimal benefit from 2 to 4.5mg....whichever is your dose. I was on 3mg for 3 yrs, before being able to go up to 4.5mg.
With LDN, more is not better. As a matter of fact, if you go over 5mg, for instance, it would be counterproductive, as your endorphins would be blocked for too long of a time and endorphins would not reproduce.
LarryLDN has been on LDN for over 5 years and he stayed at 3mg. 4.5mg was too much for him.
Go back to 3mg, where you are comfortabvle and don't worry about going up, until or if you are comfortable with it.
Quote:
Originally Posted by herekitty1960
Cherie and/or Sally.....I have a question for you. What is the optimal level of LDN to take? Are you getting the maximum benefits when you just take 3.0 or must you take 4.5 to obtain the maximum protection and benefits from it?
I have moved up to 4.5 and think I am tolerating it pretty well. I have noticed that my right knee is much stiffer and I have a harder time moving in the morning when I am on 4.5. I didn't notice any of this when I was at 3.0. Should I just "tough it out" and it will go away eventually? I want to take the dosage that I'll get the maximum benefit from so if this will pass I can wait it out. Also, I am sleeping much more than usual. Could possibly be this flare I'm in that's causing it....but I can get up at 6 AM, go back to bed at 8 AM and sleep until 11 AM....then be ready to lay back down at 3 PM and take a nap!! Let me just add that I don't sleep well during the night and I'm up and down several times.
I won't know until probably tomorrow what the results of my MRI are....I'm so hoping that there is no new activity and all this carp is just stemming from an old lesion deciding to act up.
Thanks!!
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