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Old 10-10-2008, 11:09 AM
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
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mrsD mrsD is offline
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mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb sustained release tablets...

may be made from a matrix, in which the active compound is imbedded. It slowly releases it into the GI tract, but the matrix itself DOES NOT dissolve.

It is then eliminated and may look like it did when it went in
because it has absorbed water.
We call these casts "ghosts", and they are very common.

They occur with many drugs too. One dosage form used for Covera HS, Procardia, have a tiny hole in one side where the drug comes out. This passes as an empty shell when it is done.

Sometimes compounds with a thick outer coat may also appear as casts (ghosts). These rupture and release, then fill with
other stuff as they move thru the GI tract and out. I remember many years ago my husband was using an enzyme product which is no longer available...called Festalan. When he found a cast in his stool, he was very concerned as well.
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"Thanks for this!" says:
mistiis (10-10-2008)