Here is a study continuing to show benefits of benfotiamine in diabetic neuropathy:
Quote:
Int J Clin Pharmacol Ther. 2005 Feb;43(2):71-7.Links
Erratum in:
Int J Clin Pharmacol Ther. 2005 Jun;43(6):304.
Benfotiamine in the treatment of diabetic polyneuropathy--a three-week randomized, controlled pilot study (BEDIP study).
Haupt E, Ledermann H, Köpcke W.
Saale-Klinik, Bad Kissingen, Lindenfels, Germany. BfA.Saaleklinik@t-online.de
OBJECTIVE: The aim of the study was to evaluate the efficacy of benfotiamine administered over three weeks (allithiamine; a lipid-soluble vitamin B1 prodrug with high bioavailability) to patients with diabetic polyneuropathy in a randomized, placebo-controlled, double-blind, two-center pilot study. MATERIAL AND METHODS: Forty inpatients (23 male, 18 female, age range 18 - 70 years) with a history of type 1 or 2 diabetes and polyneuropathy of not longer than two years, were included in the study. Twenty Patients received two 50 mg benfotiamine tablets four times daily and 20 patients received placebo over the three-week study period. Two clinical units were involved with 10 patients receiving placebo and 10 patients benfotiamine in each. The neuropathy score according to Katzenwadel et al. [1987] was used to evaluate symptoms of polyneuropathy, vibration perception threshold and both the physician's and the patient's own assessment were documented. RESULTS: A statistically significant (p = 0.0287) improvement in the neuropathy score was observed in the group given active drug when compared to the placebo-treated controls. There was no statistically significant change observed in the tuning fork test. The most pronounced effect on complaints was a decrease in pain (p = 0.0414). More patients in the benfotiamine-treated group than in the placebo group considered their clinical condition to have improved (p = 0.052). No side effects attributable to benfotiamine were observed. The differences between the groups cannot be attributed to a change in metabolic parameters since there were no significant alterations in the HbA1 levels and blood sugar profiles. The body mass index of the two groups did not differ. CONCLUSION: This pilot investigation (BEDIP Study) has confirmed the results of two earlier randomized controlled trials and has provided further evidence for the beneficial effects of benfotiamine in patients with diabetic neuropathy.
PMID: 15726875 [PubMed - indexed for MEDLINE]
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This is a newer version of thiamine Vitamin B1...it is now affordable and available at iherb.com
Start at 300mg a day, and if you find with time improvement you can reduce to 150mg/day. ( I use Doctor's Best brand).
Another supplement that will help is r-lipoic acid. This lowers blood sugar as well. If you take drugs or insulin you may need a dose adjustment "down" when you use this. 100mg/day is typical.
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Weezie looking at petunias 8.25.2017
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