I see by the drug list you posted, Mickey, that you may have bipolar disorder.
There are standard drug engines on the net, which you can plug in your drugs and read potential issues. I have some listed in the stickies here.
While hydrocodone may cause increased sedation, or cognitive impairment mixed with other drugs that also share that side effect, there is another potential reason for affecting you.
http://neurotalk.psychcentral.com/thread54633.html
It has been known for a while that some people with OCD or refractory depressions react favorably to opiates. This is not well understood yet, but involves the mu receptors in the brain. Opiates vary also in this effect. For example, some opiates, (oxycodone more so than others) also release serotonin in the brain, which is similar in action to antidepressants.
Here is a drug checker with the lithium/ibuprofen interaction explained:
http://www.drugs.com/interactions-ch...=1310-0,1477-0
Quote:
MONITOR: Several case reports and small studies suggest that some nonsteroidal anti-inflammatory drugs (NSAIDs) may increase serum lithium levels and increase the risk of toxicity. The exact mechanism is unknown but may involve inhibition of renal prostaglandin synthesis by NSAIDs. Lithium toxicity has been reported during concomitant use of indomethacin, ketorolac, mefenamic acid, and piroxicam. Lithium plasma concentrations have been shown to increase in healthy subjects or patients taking various NSAIDs including celecoxib, diflunisal, flurbiprofen, meloxicam, naproxen, and valdecoxib. Limited data suggest that sulindac may participate in the interaction to a lesser extent than do other NSAIDs. Aspirin and other salicylates do not appear to interact with lithium.
MANAGEMENT: Patients who must take lithium in combination with NSAIDs should be monitored for evidence of lithium toxicity, although clinically significant interactions are thought to be rare.
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Not all doctors know about opiates and bipolar however.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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Weezie looking at petunias 8.25.2017
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