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Old 10-21-2008, 02:19 PM
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lady_express_44 lady_express_44 is offline
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Join Date: Aug 2006
Location: Vancouver, Canada
Posts: 3,300
15 yr Member
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Quote:
Originally Posted by Av8rgirl View Post
If I remember correctly from the information that I have, pre-treating with benadryl and/or claritin (or something similar) is at the discretion of the treating physician. It's not in the protocol.
I think you are correct, Cheryl. According to this FDA site, there are two major warnings with Tysabri . . .

"Do not receive TYSABRI, if you:

. have PML
. are allergic to TYSABRI

. Allergic reactions including serious allergic reactions. Symptoms can
include:

. hives
. itching .
. trouble breathing
. chest pain
. dizziness
. chills
. rash
. nausea
. flushing of skin
. low blood pressure"

http://www.fda.gov/cder/foi/label/20...104s015lbl.pdf

However, I am aware (even from our Tysabri thread here), that a lot of people are advised to take antihisitimines before they are infused, so undoubtedly some allergic reactions will go unnoticed (be "masked" by the the antihistimines), especially if they are not very serious or persistent.

Cherie
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