It depends on what is going on with you.

If your GI upsets are due to low acid, which then messes up protein breakdown in the stomach, then taking Betaine and
an enzyme that has proteases in it may help.

Gall bladder issues may be slow movement of the bile, sluggish etc. Taurine, an amino acid, at 1000 mg/day may help this.
It improves bile flow.

This enzyme product was the best I could find at one time.
I used it for a few months for my GI issues about 3 yrs ago:
http://www.nowfoods.com/?action=itemdetail&item_id=3112
They helped, but in my case the problem was a fructose intolerance and by removing fructose from my diet, the gas and other nasty symptoms went away.
This product almost compares to RX enzymes given to people with pancreatic disease or cystic fibrosis. It has some other things added, like the oxbile extract (for people with no gall bladder), and bromelain etc. This product is available from iherb.com

The Cipro problem is another thing. I have a thread about damage to nerves by Cipro and how to get better from that:
http://neurotalk.psychcentral.com/thread54985.html

I think you could reduce the B-complex to 50mg size. 100mg is pushing it, for the B6 content.

I have found with aging I have to do Beano when I have vegetables now, and Lactaid for ice cream. I use Lactaid milk with 50% extra calcium for my milk now. I have lactase high dose fast dissolve tablets for non-Lactaid milk or ice cream, and I carry them in my purse.

Milk never used to bother me, but now it is beginning to.
I cannot tolerate gas, since I have a birth defect that is twisted intestines. I will have an obstruction if I don't watch the gas issue, carefully. So I keep simethicone on hand just in case.

Not every enzyme product will work for everyone. I think people are very unique when the GI system starts to malfunction. So some trial and error is to be expected.

If you have constipation, with sluggish bile flow, there is an herb called Yerba Mate, that can help this. It is basically a tea, very popular in S. America. I use the organic one (unsmoked and safer) by EcoTeas. (you can find them easily online). There is a capsule form called Green Mate, which is more convenient, by Jarrow. I find this very helpful when my gall bladder acts up.
There are studies on PubMed about Yerba, that are very positive as well.
http://www.iherb.com/ProductDetails....1&pid=194&at=0
This product is far stronger than green tea in antioxidants. And it is a Godsend for some GI problems.
It will mildly improve constipation without cramping or diarrhea, and also if you take it every day,
will improve mood to some extent! Some doctors now even recommend it. So Google it a bit, and please only choose the GREEN unsmoked variety. Time has shown that smoking to dry the herb, destroys many of its benefits. Some S.American countries use this tea instead of coffee, and some very heavily. I found one capsule of Green Mate or 1 teabag size serving of the tea to be sufficient for my needs. Many stores still do not carry the tea, so I order online with EcoTeas directly.