I have been looking for a long time for a solution to this troubling side effect. No one is making public any study to explain the weight gain with gabapentin and Lyrica.
Both drugs are not appreciably metabolized by the liver, they are excreted whole by the kidney. I believe that most of the weight gain is fluid retention.
However, taking diuretics does not improve this, and diuretics have negative side effects of their own, and do not offer much of a solution.
Also not all people get this side effect. But many do. Whatever makes some immune to this effect remains unknown.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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Weezie looking at petunias 8.25.2017
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