Simplified SUMMARY one-two-three.
1-ONE. MMP-9s eat holes in the Blood Brain Barrier(BBB), they destroy myelin and cleave/inactivate Interferon drugs.
http://home.ix.netcom.com/~jdalton/Yongrev.pdf
http://www.cnsforum.com/commentedite...9/default.aspx
2 -TWO. REDUCE MMP-9s ANY way you can - using diet, supplements & secondary effects of other drugs.
It is a matter of risk, lifestyle, costs, personal preference and your ability to make decisions based upon incomplete and admittedly weak info.
Things that reduce MMP-9s (AKA gelatinase B)
QUERCETIN..........................REDUCES MMP-9s
VIT D3 .................................REDUCES MMP-9s
RESVERATROL (Grape Skin Extract) ...REDUCES MMP-9s
(NOT Grape SEED Extract)
GREEN TEA EXTRACT(EGCGs)... REDUCES MMP-9s
ALPHA LIPOIC ACID (R-lipoic/ R-Dihdro-LipoicAcid) ... REDUCES MMP-9s
NAC N-Acetyl-L-Cysteine .......REDUCES MMP-9s
STATIN DRUGS (i.e Zocor) .....REDUCES MMP-9s
Omega-3s (ie Fish oil) ...........REDUCES MMP-9s
Minocycline/Doxycycline.........REDUCES MMP-9s
Curcumin.............................REDUCES MMP-9s
Pycnogenol (Pine bark extract)..REDUCES MMP-9s
Chondroitin sulfate (CS) and CS plus glucosamine sulfate (GS) ..REDUCES MMP-9s
Interferon Betas 1a/1b...........REDUCES MMP-9
(of course Steroids ....REDUCES MMP-9s)
***NOTE*** ( gelatinase B = MMP-9) ***NOTE***
3-THREE. Cap other inflammatory components like IL-12, Gamma Interferon, TNF-a, IL-1 beta and glutamate excitotoxicity.Some of the above "things" also lower some of these. I will try to elaborate on this but I want to stay on the MMP-9s focus for now.
http://home.ix.netcom.com/~jdalton/ms-two-stages.pdf
jackD
p.s. Sorry but understanding how MS progresses, a technical medical thing, is somewhat necessary to understand and appreciate this complementary approach. How MS progresses will be another NEW future thread. I am not concerned with the ULTIMATE CAUSE OF MS but only with how it progresses and the few processes that can be slowed to alter the disease progression.