its hard to say and depends on which school of thought you follow. the general ida is that the LDN can interupt the progression of the MS and what ever symptom relief you get is a bonus. for me, my fatigue level is way better than before the ldn. i have a coworker who is now using the LDN for her MS too and she tells me her ON is clearing to the point where she can read things on the television again.