the individual 'minor' symptoms all add up a quality of life issue.for example; what good does it do to be fully mobile if being mobile gets you exhausted just moving around the house or even getting dressed in morning? for some people thats a big deal. or like with me the spasticity that was so bad in my hands that i couldnt even tie my own shoes or put up my own hair. for me that was a biggie.
not eveyone is going get the same bennefits from LDN, but not everyone gets the same bennefits from the CRAB drugs either. not to mention that none of the CRAB drugs promises anything more than what the LDN seems capable of doing.it was once explained to me like this: think of your body as an orchestra. as long as everyone plays their part of the score on time, on cue and in key it all works and everything sounds fine. with an autoimmune illness,like MS, your conductor is kermit the frog after a two week coke binge. hes giving bad signals, hes telling woodwinds to play brass and strings to play woodwinds. his tempo cues are way off and nobody knows what hes doing. with the LDN its like changing kermit out for leonard bernstien. and hopfully you can go on from there for the better.the down side being the damage done is damage done. you cant un ring a bell. the idea with the LDN being (as i understood it) people with MS are low on endorphens anywany. when taken at a strategic dose( hence the 'lowdose' part)and taken at a strategic time of day (usually around bedtime, between 9pm and 3am) you can trick you body into making more endorphens. the endorphens are believed to be,at least in some part, responsible for helping to regulate the immune system. more endorphens meaning a better regulated immune system and in turn meaning that the immune system would stop doing the things that produce MS.( some people think that the problem isnt so much an over active immune sysmtem, but a poorly regulated one).for some people it can even give the body a chance to start doing some repairs to the damaged nerves.but theres no guarentee. theres only been very limited and spotty clinical study into the myriad bennifits of LDN in MS. theres only been 3 or 4 small studies that i know of. but theres a whole laundry list of auto immune things people are useing the LDN for.at least with the LDN theres some idea of how it may work. as i remember it, they have no solid ideas about how the copaxone works. it just seems to work for some people. like i said before, none of the crab drugs promise to stop progression. they dont even promise to sloe it down. the copaxone only said the it 'can' decrease the frequecy and duration of exaserbations. not that it will. the tysabri had some issues in the beginning.the avonex and the beta serons are about on the same par. theyre all injectsbles where the LDN is a pill or capsule. myself, i take 3 small capsules once a day at about 9pm. nothing else. no baclophen, no ditripan, no prenisone, no colace,xanex,amantadine nothing else. and i seem to be doing better with my MS than people i know with comparable progression who do the injections every day and then swallow a medicine cabinets worth of other drugs to help with the side effects of the injections. did i mention the price tag? even eithout insurance i would only pay 25$ a month for the LDN. as it is i only pay 15$. copaxone,list price, off the shelf from the walgreens at smithville & watervliet in kettering, ohio........last i asked,back in august was 2815$ a month