For me personally, I'm hesitate with all these "newer" drugs. For my body, the old standbys seem to work the best. Tramadol didn't do a thing for me, like taking sugar pills. Fentinel patches are fancier, but almost had my wife collecting the life insurance. Good old Methadone works just fine for me. I take Neurontin as well (3600mg a day), and this combo seems to work fine for me right now. Time will tell what dosages and meds are in my future, but I always tell the docs now, "let me try the old stuff and see how it works first". Isn't going to win over their Pharmasuetical Reps, but oh well! :-) And generally, they are cheaper, usually covered my insurance, and may even have a generic equal.

But as said before, everybody is different and different things work for different folks.

Jay