Thread: rigidity or bradykinesia
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Old 11-20-2006, 10:21 AM
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I looked for a reference that contained all three words. So, far this is all I could find. It does answer the question. I don't agree with the tremor part though...my personal feeling since mine gets worse all the time.

Neurosurgical Medical Clinic, San Diego, CA

http://www.sd-neurosurgeon.com/diseases/pd.html

Excerpt:

The introduction of L-dopa in the 1960's brought a marked reduction in stereotactic surgery for PD. L-dopa alleviates bradykinesia, rigidity and tremor, allowing patients to improve in activities of daily living. Its combination with carbidopa (as Sinemet) reduces severe side effects and revolutionized the medical treatment of PD. Unfortunately, after many years use, higher doses of Sinemet are required. Many patients develop jerking and writhing movements (dyskinesias) and rapid, unpredictable fluctuations in symptoms (on-off phenomenon) as well as other side effects. The short amount of time Sinemet lasts after oral dosage, and interference with its absorption from the stomach by food protein further complicated its use.

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