I've had one in 18 yrs. Like Sally said, if they suspected it wasn't MS causing any new problems, that is when I would have another. Other than that, what's the point?

I think they are getting closer to defining the "risk for future disability" through evaluation of our gray matter damage, but that is a new concept and not currently a "marker" for efficacy of our meds. "Witnessing" transient enhancing lesions, apparently doesn't matter to long-term (10+ yrs) progression anyway.

If we are not succeeding with our med of choice, that should be most obviously evident by our disability progression.

Cherie