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Old 11-23-2008, 11:41 AM  
Wise Elder
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Join Date: Aug 2006
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"Curcumin is a natural phenolic component of yellow curry spice, which is used in some cultures for the treatment of diseases associated with oxidative stress and
inflammation. Curcumin has been reported to be capable of preventing the death of neurons in animal models of neurodegenerative disorders, but its possible effects
on developmental and adult neuroplasticity are unknown. In the present study, we investigated the effects of curcumin on mouse multi-potent neural progenitor cells (NPC) and adult hippocampal neurogenesis. Curcumin exerted biphasic effects
on cultured NPC; low concentrations stimulated cell proliferation, whereas high concentrations were cytotoxic. Curcumin activated extracellular signal-regulated
kinases (ERKs) and p38 kinases, cellular signal transduction pathways known to be involved in the regulation of neuronal plasticity and stress responses. Inhibitors of ERKs and p38 kinases effectively blocked the mitogenic effect of
curcumin in NPC. Administration of curcumin to adult mice resulted in a significant increase in the number of newly generated cells in the dentate gyrus of hippocampus, indicating that curcumin enhances adult hippocampal neurogenesis. Our findings suggest that curcumin can stimulate developmental and adult hippocampal neurogenesis, and a biological activity that may enhance neural plasticity and repair."
Mrs. D. The only part of the above paragraph that I understood was where it mentioned hippocampal. (This refers to short term memory right??) Or am I dead wrong here?

If this curcumin helps THAT, I'll go out and buy some tomorrow.

But do me a favor. Talk to me like I'm brain dead and translate the rest.

For example.

What this means is that if you use curcumin in your diet, you'll have a better memory, live longer, etc.

Because I couldn't understand ANY of it. I feel like a dodo bird among swans.





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